I'm lucky as I have only 3 injuries thus far. 80/100 does seem a bit high tbh, but this should be factored in when you set your positional %age sliders (fatigue level).
I think 60-65% is more realistic for injuries, and given the fact we don't have practice squads in the game, it might actually have you hunting a dried-up FA market to replace serious injuries.
One final note on injuries - I genuinely believe that the league injury level should be toned WAY back for any pre-season games.